The food and drug administration fda first approved chloroquine in 1949.
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plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug dmard .
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another open question remains the influence of the duration of drug exposure, as it has been shown that chloroquine hydroxychloroquine has cumulative effects 67 .
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alot of the concerns are related to the problems caused by chloroquine, the predecesor to hydroxychloroquine plaquenil .
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